The Industrial Phase-Transfer Catalysis Experts

PTC Tip of the Month E-Newsletter

PTC Contract Research


1DarrellAtHoodCustomer Benefits: Increase R&D performance with the fastest timeline by having PTC Organics Inc. design and execute an experimental program to evaluate a PTC process breakthrough for your reaction. PTC Organics Inc. invests its best efforts, laboratory resources and highly specialized expertise of PTC Organics Inc. in industrial phase-transfer catalysis to determine the feasibility of a PTC process breakthrough to meet specific performance targets determined by the customer. PTC Contract Research is justified in cases in which time is of the essence and the best available expertise is required to reach firm conclusions quickly. During PTC Contract Research, Dr. Marc Halpern personally designs and redesigns the experimental program on a daily basis to reach the maximum number of firm conclusions per experiment. Dr. Halpern has 38 years of experience in PTC, 30 of which are in industrial PTC. PTC Contract Research typically takes 4 weeks of laboratory time to determine breakthrough plus one week to compose a highly detailed report of all experiments, underlying rationale behind each experiment and results. PTC Contract Research Process should be used instead of PTC Process Consulting when the customer’s timeline is tight or the customer does not have available laboratory resources to execute the experimental program.

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Customer Applications: Improve process performance in ALL stages of process development and plant support including route selection, process development & scale up, retrofit of non-PTC processes with much more profitable PTC processes and optimization of existing PTC process.

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Reaction Types: PTC excels in more than 30 reactions types in the broad categories of strong base reactions, nucleophilic substitutions, oxidations, reductions, transition metal co-catalysis and strong acid reactions. Examples of reaction types in which PTC excels include: O-Alkylation (Etherification), N-Alkylation, C-Alkylation, S-Alkylation, Dehydrohalogenation, Aldol Condensation, Wittig, Michael Addition, Darzens, Carbene Reactions, Esterification, Transesterification, Displacement using: Cyanide, Fluoride, Azide, Hydroxide, Thiocyanate, Cyanate, Sulfide, Sulfite, Iodide, Nitrite, Nitrate. Oxidation, Epoxidation, Borohydride Reduction, Hydrogenation, Carbonylation, Chloromethylation, Hydrohalogenation, Reactions of HCl/HBr, Polymerization, Polymer Modifications and more.

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Why Should You Work With PTC Organics Inc.? PTC Organics Inc. is the only company dedicated exclusively to developing and commercializing low-cost high-performance green chemistry processes using phase-transfer catalysis. PTC Organics Inc. has unmatched experience working on more than 100 commercial PTC development projects under secrecy agreement with chemical companies manufacturing pharmaceuticals, agricultural chemicals, monomers, polymers, petrochemicals, flavors & fragrances, dyes & pigments, solvents, high energy materials and other specialty, fine and commodity organic chemicals. PTC Organics Inc.’s highly specialized expertise in industrial phase-transfer catalysis encompasses all aspects of process development from initial screening of breakthroughs through workup, catalyst separation and recycle when required.

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